Born on 3 August 1971 in Belgrade. After finishing high school, he entered the Faculty of Medicine in Belgrade, from which he graduated in the academic year 1996/97. The following year, he completed his internship at the Clinical Centre of Serbia, after which he chose general surgery as his area of specialization at his home faculty and passed the specialist exam in 2003. During his studies, but also after their completion, he participated in the creation of several scientific research papers as an author and co-author.

He enrolled in doctoral studies in the field of medical epidemiology in 2008 at the Faculty of Medicine of the University of Belgrade, and defended his doctoral dissertation in 2015.

He completed a specialist course in hepatobiliary surgery in 2001 in London at Hammersmith Hospital, where he continued his training in 2006. He completed a specialist course in transplant surgery at King's College London in 2011, and during 2012/2013 he received specialized training in the field of liver transplantation surgery at Clinical Hospital Centre Merkur in Zagreb.

He was elected to the position of clinical assistant for the subject of surgery at the Faculty of Medicine of the University of Belgrade in 2012, and to the position of assistant professor in 2019.

He works at the Clinic for Emergency Surgery of the Emergency Ward of the Clinical Centre of Serbia, and from 2010 he was the head of Intensive Care Unit in the Department of Surgery I. He was the director of the Emergency Ward of the Clinical Centre of Serbia and assistant director of the Clinical Centre of Serbia for medical issues from August 2012. He was appointed head of the Department of Transplantation in 2013.

During his tenure as director of the Emergency Ward of the Clinical Centre of Serbia, he formed the Department for Liver Transplantation and led the team that performed the first liver transplant in the Emergency Ward. He founded a multidisciplinary oncology council, formed the Department for voluntary blood donation, as well as the Trauma Centre of the Emergency Ward on Kopaonik. With his personal commitment, he contributed to the acquisition of necessary medical equipment in the Emergency Ward.

He was elected to the position of Minister of Health of the Republic of Serbia on 27 April 2014, 11 August 2016, and 29 June 2017. He held the same position until October 2020, and then in the mandate until October 2022 too.

He speaks English.

He is married and is the father of two children.

Zlatibor Lončar